Hi jroc and Simply Southern,

If you fit our 23andme ERAP1 data to the table in the above paper we should be able to guess what allotypes we have.

The five main SNP's in 23and me are rs2287987 (M349V); rs30187 (K528R); rs10050860 (D575N); rs17482078 (R725Q) and rs27944 (Q730E)
It's pretty simple for me and Simply Southern - we have two of the normal functioning *002 allotypes, that is amino acids MKDRQ for both our ERAP1 versions.

jroc on the other hand has one and possibly two hypofunctional alleles.


Dx Oct 2006 B27+ undifferentiated spondlyarthropathy (uSpA) with mild sebhorrhoeic dermatitis and mild Inflammatory Bowel Disease (IBD) controlled by NSD since 2007.