Kickas.org Forums Ankylosing Spondylitis General Discussion #1 AS Web Support Group Anyone use diclofenac?

I have been taking it for a couple of weeks Starting to have a lot of problems with my stomach rolling and diarriah. I'm thinking it might be from this med

Been prescribed it a couple of times, no ill effects, but nothing beneficial either.
J.R.

I'm with Oldtimer. Took it a long time ago to no avail.

Could easily be that. NSAIDs can hit your gut hard.. Having said that, Diclofenac was the one I tolerated for the longest, but then I did take the extended release form of it (so it kind of bypassed my stomach before starting to absorb and I didn't get the heartburn type pains).

Diclofenac - Hmmmmm. Did a vile number on me. Hellish stuff - diarrhoea and all the rest - never again with those NSAIDs for me !

I about to quit it. I don't think it's doing much for. Me. My Rheumy wanted me to start taking anti inflammatory again along with the enbrel. I quit them once I started enbrel. I was off of them for about 3 months. No constipation during that whole time. As soon as I started them back. Here we go.

Hello, Bax1:

This drug, in particular, greatly accelerated my AS; I took Voltaren for at least four years and had terrible spontaneous bleeding ulcers. More intestinal lesions equals more AS activity, in addition to proctitis, GERD, and myriad other things I got related to AS and especially advanced due to the damage caused by this drug.

I would not touch it with my worst enemy's tract, and have not even taken an aspirin during the previous 15 years; coinciding with my total remission.

HEALTH,
John

Not orally, but I use flector patches, which are dichlofenac, over my SI joint.

I'm on Humira, but my SI joint still needs a bit of help, maybe due to the damage caused over the years by the inflammation, anyway over the SI joint, changed every 12 hours, it helps.

I started doing that because NSAIDs tend to give me edema and/or gastritis, or they are too mild to do much good at all, but the one's strong enough to help, give me the side effects, if taken internally (I've tried almost 10 of them, a dozen if you count the cox2 inhibitors (celebrex, vioxx when it was on the market…both gave me side effects).

I also have a topical triple NSAID creme/gel that the compounding pharmacist whips up for me (with prescription)…its called KIP (ketoprofen, ibuprofen, piroxicam)….he suggested it…said orthos, etc prescribe it for patents….I don't use it often, but use it on my neck when needed, as its hard to use other things like ice/heat/ultrasound there.

But no more oral NSAIDs or cox2 inhibitors for me, except maybe an Aleve now and then for a day or two, but that's it. Been there, done that, side effects outweigh the benefits for me. But I gave it a good try first.

It has put me in remission for weeks(multiple times). I had to use extra-gi meds. It has flared my AS too. I think taking infrequently for pain is ok but you need a week or 2 of constant use to be anti-inflammatory. They are the only other thing proven besides the TNF blockers and much less so IL-17. I'm going to see dr reveille in April. Not sure I would still need my appointment by then but would love to meet and talk with him and maybe even have him on my team. Before the TNF blocker started to work my dad was in contact with their office. I tried to get in there years ago with no success.

But anything that has the ability to flare my AS makes me weary.

And I'm going to ask his opinion on the NSAIDs. I do not even trust asking my current doctors because a lot of times they go off the lit. Which can misleading and down right wrong.

I will be interested in hearing about you visit with Dr Reveille.