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Joined: Sep 2015
Posts: 303
Likes: 2
Joined: Sep 2015
Posts: 303
Likes: 2
The relationship between the gut and neuro-immune system fascinates me. Environmental triggers like bug bites can trigger autoimmune disease too by introducing a chronic infection. I would like to believe that if the trigger is removed then the body will restore a healthy genetic expression. It seems to work in some cases. Perhaps in some cases the microbial trigger in the gut has migrated into the cells of other organs thus making diet ineffective.

When I first started getting AS symptoms in 2015 I argued with the doctor emphasizing that the trigger is related to using ibuprofen. I suggested that it interfered with gut function and allowed my immune system to be over stimulated by gut bugs. He said that there is no association between bacteria and AS. One day in 2017 I went to the hospital and he was no longer available. I was told that he went abroad to do research in the relationship between AS and the gut.

Auto-immunity is strongly sex-linked to the X and Y chromosomes, having been pregnant, fertility rate of a population. Any guys here develop AS after getting pregnant? LOL!!

Why Do Women Have More Autoimmune Conditions?

I have used gelatin as a collagen source in general for all connective tissues, not just the gut. Someone recommended that I just use a more concentrated and absorbable powder. I guess either is a good source and can't hurt if eaten every day. I'll go have some gelatin now.


HLA-B27 neg, vague AS symptoms in 20s and early 30s
1993:fibromyalgia (age 25)
2013.07:Reverse blockage in a SCUBA accident
2013.08:Scratched by a sick cat
2013.09:Strange sore throat then meningitis
2014:Chronic inflammation at the base of the skull
2014 to early 2015:excess NSAID use developed complete axial inflammation, included psoriasis
NSD helped well and but was not perfect
2018.07: weak +'ve tests for borrelia, babesia, bartonella and mycoplasma pneumonia using Armin Lab, ANA=equivocal
Joined: Jul 2013
Posts: 168
Likes: 2
L33 Offline
Joined: Jul 2013
Posts: 168
Likes: 2
I think the mechanism to remission lies in clearing out a barstard chronic bacterial pathogenic infection which triggers us with A.S and a combination of healing our GUT linings though what ever method helps, like FMT, antibiotic Protocol(AP), Tumeric spice powder Enemas, Gelatin Enema....

HLA B27+
Have AS since the age of 13.
Diagnosed in 2005 at the age of 22

1 member likes this: Robin_H
Joined: Nov 2001
Posts: 18,156
Likes: 6
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Joined: Nov 2001
Posts: 18,156
Likes: 6
Robin, your thought are interesting. I would point out to you, however, that AS can develop in childhood. I know I was showing early signs by the time I was 14. I ate an extremely healthy diet, was active and young. And at the chiropractor for the pain in my back. Other members here developed it at a younger age, as well. It is genetic, don't forget, and tends to run in families. As does the Crohn's Disease that I also live with. Both come down my mother's line, AS on on her father's side and Crohn's on her mother's side.

I do think there is a gut link involved, but I could hardly have been showing signs of that at age 14. When I say 'healthy' I mean 'uber-healthy'. No refined anything, very small amounts of red meat, lots of fresh veg and fruit, no cakes, no cookies, no potato chips, no candy, no pies, unless it was a special occasion. There was no 'trigger' for my Crohn's as there were aspects of that that I experienced as a young child (recognised in hind sight, which we all know is 20/20); although I did slip on black ice when I was twelve and landed on my tailbone, which I've often wondered was the trigger for the AS.

As to ibuprofen ... again, in my own case, I was not using high levels of pain killers of any kind as a child and young adult. That didn't start on a regular basis until I was in my late thirties. Not that I didn't need them; just didn't take them on a regular basis. I already had both Crohn's and AS fully blown by the time I was in my early 20s, but it flared then backed off. As a student of performance and dance, I injured myself all the time. I put my pain down to that. You have to be taking a lot of ibuprofen for quite some time for the gut to be impacted. I am sorry to hear that you feel it triggered your psoriasis. It can happen that way, I've read.

Considering that the ratio of male cases to female cases of AS is about 7:5 at this point, I'm wondering about your comment on pregnancy -- I do realise you were having a bit of a joke, but it indicates that you think pregnancy is a trigger? It might be for some, I suppose. But I've never been pregnant, so it doesn't apply to all.

And there is my cautionary note. Your case of AS, its progression, its triggers, is yours - nobody else's. Sadly, my triggers cannot be 'removed'. The AS and Crohn's are with me to stay. I have never achieved full remission, despite everything I've done to help myself. Some people do. Perhaps you will be one of those and I hope so.

Love and light.


A life lived in fear is a life half lived.
"Strictly Ballroom"

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