Hello:

I have just administered my first injection of enbrel, and so far so good.
I was just wondering how and when people started responding ?

The nurse estimated 2-4 weeks, and thoughts ?

Cheers

Pasch

Each person will react differently but that's generally pretty close. For me it was about 4 weeks or so. Been taking it now since late Feb and the results have been incredible. Just stay patient for a few weeks before passing judgement.

Glenn

Took me about a month to get decent results, and 2 months for the full effect.

How are you doing now?

I have just given myself my 4th injection and am not really feeling any effect yet, other than several bouts of dizziness. The more I read about Enbrel and possible side effects, the more I am not sure I want to stay on it.

I have been on Enbrel for one month...not feeling it yet. Are you concerned with the possible side effects?

That sounds about right. For me it was probably closer to the two week end of that window.

For me it took about a month before it kicked the AS. I was sleeping so much better, and I just felt really good. After about 7 months the MS started to kick in. I still had no pain, but I was dizzy all the time, and my right foot didn't hit correctly when I ran. Then I couldn't run at all. They sent me for a bunch of tests, and then said you have MS. That was the end of enbrel for me. I don't tell you that to scare you because the doctor told me that MS and enbrel are very rare. I just happen to be one that is built so that enbrel will bring out MS.

Hi... I think I started to find a little relief by 4 weeks, but after 12 weeks it's really marked. I am feeling almost nothing in the low back/SI, except if pressure is applied. I do have a lot of stiffness though and my SED is still at 40?! I don't know if it will ever get down any lower?
Have others experienced a quieted SED rate after TNF treatment?

Hell, I don't even know what an SED rate is?

AKA ESR (i believe). It's a blood test that measures inflammation in the body. It is not necessarily predictive of anything in particular but it seems to be a pretty hard to ignore red flag that something is amiss.
Once they figure it's arthritis it is one of the standard tests that are done. My lowest was 34 and hightest was like high 50s...
I notice you're from Canada and it is certainly possible that it's called something different there. Also this is just stuff I picked up along the way... Not like any doctor ever sat me down and gave the exhaustive run-down.... lol
Anyway I have a friend with AS whose SED rate is never elevated -- so its just curious really
Take care, Jess

I started on remicade in July. My ESR was over 80 in November and in April. After 2 remicade infusions it was down dramatically to 15. No wonder I am feeling so good! Anti TNF has done wonders for me - more than I had hoped for.
I wish you the same success.

Right before I switched from Enbrel to Remicade earlier this year, both my SED rate and my CRP were through the roof. The SED rate was 70 in back-to-back months, and the CRP came in at 81 and 82 those same months--both readings are absolutely through the roof, and among the highest I have ever had for either test. Well, after just one dose, by CRP had dropped back to 1.4, which is in the normal range, and the SED rate had fallen back to 32. That is still high, but a drastic reduction nonetheless.

So, in answer to your question, yep, I experienced dramatic reductions in both SED and CRP thanks to anti-TNF treatment. I get my fourth or fifth Remicade treatment tomorrow, and I still feel fantastic, knock wood.

Brad

Go figure? I'll ask my doc about that and see what sort of numbers they come up with. Kind of reminds me of how they added that "metachlorians" nonsense into the Star Wars movies...as if you could quantify spiritual power?

jess, aloha

at various times sed/esr as high as 78
often in the forties...over many many years of nsaids.

now down to about 12 after four years doing enbrel...one time it was even lower.

good luck
keep shootin'