OK, I know that you have all heard me rave about how I feel so much better with the Enbrel. My back, hips and chest hardly ever give me any grief anymore. However, recently my feet, ankles, hands and wrists have all been very sore. I can tell that it is AS related, because the pain is the same, just in different spots. Has anybody else had this happen to them. It's almost like the AS is telling me "ah ha, you stopped me from hurting you in the normal spots so now I'm going to attack new spots". Anyway, I'm just curious if anybody else has had this happen or if any of you have suggestions. Thanks much!!!