Does it make your joints feel loose at all? Weird I know to ask. I am newly diagnosed with AS and I have had a lot of trouble with my hands, knuckles with imflamation. Nothing you can see, but it does give me trigger fingers. My hips, knees and elbows do have a full feeling (and I have not started any treatment yet), and in my case I think this is what causes me say they feel loose. I also wake up at night with my eyes puffy. . .