Of four children in my family, only I have AS. I have three children, and none of them have AS (they are in their 20s). Of my 10 nieces and nephews, only one has AS. The odds of getting AS are low, even with being HLA-B27+.

And, even with having AS, I am leading a productive and fulfilling life. I prefer to have been born and getting AS than to never having been born at all! And with NSD, my AS pain has diminished greatly, so I am having an enjoyable life again.

So, don't let the thought of passing along AS stop you from having children.

AS symptoms started 1991. Official dx in 2006 with HLA-B27+, fused SIJ, bone spurs in back, extreme rib/hip pain, and other family with SpA. Started Enbrel in 2006 with good results, but stopped in 2010 due to nerve damage (MS) from it. Getting good results with no-starch diet since 2011.