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#486043 03/24/13 04:22 AM
Joined: Feb 2006
Posts: 1,483
drizzit Offline OP
Silver_AS_Kicker
OP Offline
Silver_AS_Kicker
Joined: Feb 2006
Posts: 1,483
Fascinating article on how Borage and fish oil together really impacts IL 17 inflammation pathway.

IL 17 is a big player in AS. this is a pdf


http://www.jbc.org/content/284/23/15400.full.pdf


No families take so little medicine as those of doctors, except those of apothecaries.

Oliver Wendell Holmes
Joined: Nov 2001
Posts: 18,187
Likes: 7
Very_Addicted_to_AS_Kickin
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Very_Addicted_to_AS_Kickin
Joined: Nov 2001
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Very very interesting. Thanks Drizz!!

Warm hugs,


Kat

A life lived in fear is a life half lived.
"Strictly Ballroom"

Joined: Jan 2008
Posts: 21,346
Likes: 2
Very_Addicted_to_AS_Kickin
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Very_Addicted_to_AS_Kickin
Joined: Jan 2008
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thanks for that.



sue

Spondyloarthropathy, HLAB27 negative
Humira (still methylprednisone for flares, just not as often. Aleve if needed, rarely.)
LDN/zanaflex/flector patches over SI/ice
vits C, D. probiotics. hyaluronic acid. CoQ, Mg, Ca, K.
chiro
walk, bike
no dairy (casein sensitivity), limited eggs, limited yeast (bread)
Joined: Feb 2012
Posts: 126
L
Journeyman_AS_Kicker
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Journeyman_AS_Kicker
L
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Posts: 126
Very interesting...How much of each do you take daily?...I take Krill oil now...but not borage seed oil....


Diagnosed with AS in 2007 Hx of episodic back pain since I was 13.
Fibromyalgia Diagnosed Feb. 2013
methotrexate and Enbrel
Started LSD Feb 2012
Vit B,C,D, fish oil, folic acid, 5HTP, Gabba,Magnessium.
I am so much more then my symptoms:)

Joined: Dec 2003
Posts: 1,368
Bronze_AS_Kicker
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Bronze_AS_Kicker
Joined: Dec 2003
Posts: 1,368
HI

I have taking Omega 3 fish oil for 25 years 6 gms a day. If I flare which is rare I increase to 8gm per day. It was a rheumatologist group in KIngston ,Ontario Canada that did a study then and I took part in it. In six weeks the swelling in all my joints settled down. It didn't stop the SI pain, and thoracic pain, but sure settled the pain down in my feet.


Janet

Joined: Jul 2010
Posts: 1,191
V
Steel_AS_Kicker
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Steel_AS_Kicker
V
Joined: Jul 2010
Posts: 1,191
Drizzit,
Thanks for the article, I liked it. How long do you think you need to take borage seed oil to notice improvements in joints?


Diet change has improved my RA. I feel best eating raw veggies and some fruits and avoiding grains, sugars, nightshades, beans and dairy. Sed rate dropped from 65 to 19, but it took over a year.
www.fatsickandnearlydead.com

excess fat/oils = pain for me
recipes for raw food on Youtube "raw food romance"
and "healing josephine" Josephine is in remission from RA after two years by change diet/exercise
Joined: Apr 2009
Posts: 96
R
Apprentice_AS_Kicker
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Apprentice_AS_Kicker
R
Joined: Apr 2009
Posts: 96
yeah interleukin 17 is one of the major players in autoimmunity in general - but more specifically autoinflammation.

Very interesting post.

Joined: Apr 2009
Posts: 96
R
Apprentice_AS_Kicker
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Apprentice_AS_Kicker
R
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Posts: 96
Drizzit as in the drow elf?

Joined: Feb 2011
Posts: 1,968
Pea Offline
Captain_AS_Kicker
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Captain_AS_Kicker
Joined: Feb 2011
Posts: 1,968
Since I am not positive for the other gene, I believe if tested, I would pop on the IL's listed for A.S. Thank's for posting.


Pea
Diagnosed with A.S. 29 year's ago.
Diagnosed with Fibro 10 year's ago.
Remicade, Intrathecal Pain Pump 2013
Joined: Jul 2012
Posts: 87
J
Apprentice_AS_Kicker
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Apprentice_AS_Kicker
J
Joined: Jul 2012
Posts: 87
From what i saw in the study , they took 800 mg of Fisher oil And about the same amount of borage oil . So the ratio should be 1 : 1
For the Time to get result, we can see in that after 4 weeks il-17 have been reduced considerably Also il-23 , the key cykotin in the spondylarthtopies.
So it worth a try .
I just began with 2000mg of each... We ll see

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