I dont know if this is any help, but I was on indomethacin for years and was worried about possible stomach ulcers etc, I put put on diclofenac suppositories 100mg at night, they take about 15 minutes to work and they are wonderful. I have diclofenac tablets 50mgs for the day, but the suppositories last in excess of 12 hours, and so far, no side effects.