With AS, there is definitely NOT a treatment that works for everyone, or even most people. Most of the treatments have some serious side effects, which you may or may not experience. Humira and Remicade are both treatments that some people here have found to work great for them. Sometimes people just have to weigh out all the risks and possible benefits. I don't even know if doctors can tell which treatment would be best for anyone, you might just have to try one and see. I take a high dose of anti-inflammatories, prednisone(which I am dosing down on) and methotrexate (an immune system repressor). Before that, I tried Sulphasalazine and it made me violently sick. Some people here take that and it works for them. I hope this helps.....

"Reality is the leading cause of stress--for those in touch with it." --Jane Wagner