Not any evidence but just a quote from pdf I posted recently about the gut/autoimmune paradigm - https://www.kickas.org/ubbthreads/ubbthre...true#Post392187

"In fact, in clinically asymptomatic Crohn’s disease patients, increased intestinal epithelial permeability precedes clinical relapse by as much as 1 year, indicating a permeability defect might be an early event in disease exacerbation."

Thanks SJLC. There are definitely many reasons to be cheerful. Even in NZ there is research being done - https://iprg.wiki.otago.ac.nz/Main_Page
"Increasingly it is being argued that a compromised intestinal barrier, particularly an increase in the permeability of the intestine, is a necessary prerequisite, not only for Inflammatory Bowel Disease (IBD), but also Coeliac disease, Diabetes Mellitus Type I (TIDM) and Ankylosing Spondylitis (AS). It has been shown for instance that in patients in whom TIDM is anticipated (positive antibodies but no clinical signs) an increased permeability can be observed without obvious intestinal inflammation." - I wish I could log in to read more about it but it won't let me create an account.

Also another researcher at the same university in NZ is looking into the relationship between AS and Crohn's - http://osms.otago.ac.nz/index.php/see-mo...isease-process-

It's good to see that some research is being done into this aspect of the disease to try and establish whether the gut is just another part of the body that is targeted by the disease or whether it may be part of the cause.

Quote:
I should probably write up a post about this study, which explores the link between gut inflammation and AS inflammation...

That would be cool if you could do that. That would be very interesting to read.