I'm on my 6th week of Cosentyx, 2 weeks since my last shot and I feel better than I have in years! You start with a series of 5 total weekly shots then go to monthly maintenance. So I'm two weeks away from my first monthly shot but it's holding strong. I was close to pain free in the first week. Yes, there's still pain and I can't walk for too long before I start to hurt, but I'm doing better that I have in years. I was unable to stay in bed longer than 6 hours due to pain prior to starting it, now I can get a good night's rest!