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Joined: Jul 2003
Posts: 2,962
Presidential_AS_Kicker
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OP
Presidential_AS_Kicker
Joined: Jul 2003
Posts: 2,962 |
Hi All,
Interesting. I found this article tonight while I was searching for something totally unrelated.
"Increased risk of developing ankylosing spondylitis among first-born children"
"Conclusion. Low birth order is a risk factor for AS in humans."
http://cat.inist.fr/?aModele=afficheN&cpsidt=842617
I'm the 2nd youngest out of 6 (the 5th one born), but I don't have a family history of AS as far as I'm told. My younger brother might have a mild undiagnosed IBD type of problem though... not sure.
James.
Last edited by JamesB; 08/23/08 07:47 AM.
HLA-B27+, JRA diagnosis in 1981, re-diagnosed as AS in 1988. Also iritis, colitis, and psoriasis. NSD + low carb helps me. My health makes it hard for me to post in a timely way.
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Joined: Mar 2002
Posts: 9,552 Likes: 10
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Joined: Mar 2002
Posts: 9,552 Likes: 10 |
Hi James,
Interesting... however my father and I both have AS and we are both the 1st of 2 children.
Tim
AS may win some battles, but I will win the war.
KONK - Keep ON Kicking
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Joined: Aug 2008
Posts: 570
Sergeant_AS_Kicker
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Sergeant_AS_Kicker
Joined: Aug 2008
Posts: 570 |
I can see how second and third litters might have fewer resources from the mother, or might inherit immune system weakness, etc. And aren't first-time parents always more careful? I have worked in medical research for many years, and it's not uncommon for researchers to notice apparently meaningingful data where there may only be coincidence. But you have to turn over every stone, I suppose!  You never know!
In the depths of winter, I finally learned that there was in me an invincible summer. -Albert Camus
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Joined: Sep 2001
Posts: 7,427
Addicted_to_AS_Kickin
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Addicted_to_AS_Kickin
Joined: Sep 2001
Posts: 7,427 |
Interesting James... I have a dx of AS and am the oldest. It's myself and my brother. My oldest Gianna has a dx of JRA as well.  My 2nd and 3rd havent shown any symptoms thankfully. 
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Joined: Sep 2001
Posts: 7,427
Addicted_to_AS_Kickin
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Addicted_to_AS_Kickin
Joined: Sep 2001
Posts: 7,427 |
Hi Molly... Good points...I am the oldest in my family and have a dx of AS. My oldest who is 14 also has arthritis. She has a dx of JRA. I was extra careful with her and my other 2 wee ones. They havent shown any signs of arthritis thankfully!
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Joined: Aug 2008
Posts: 570
Sergeant_AS_Kicker
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Sergeant_AS_Kicker
Joined: Aug 2008
Posts: 570 |
I think it's going to be very, very interesting, the more they discover about this class of illness. The immune system is so complex, and so much is not yet known -- it's fascinating! Yeah, I remember my sister with her firstborn; everything was planned, they sang all the potty songs and all the eating songs, and read about everything. By the time my niece came along, I think they were a leeetle more casual!
In the depths of winter, I finally learned that there was in me an invincible summer. -Albert Camus
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Joined: Sep 2001
Posts: 7,427
Addicted_to_AS_Kickin
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Addicted_to_AS_Kickin
Joined: Sep 2001
Posts: 7,427 |
LOL! You r very right!  With Gianna we had countless pictures. Then came miss Sofie and we had plenty of pics too..but not nearly as much. Hardly had a free moment. I wasnt tip toe'ing so much. I realized I had been overdoing it. Then came my son...Lordy..were we much more relaxed. buggy 
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Joined: Jul 2008
Posts: 6
New_Member
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New_Member
Joined: Jul 2008
Posts: 6 |
Hi James, Thanks for sharing the info. I am recently dx with AS although I think it's been there for many years. I am the oldest of 3 children, and the only one in my family dx with it. Makes you wonder? Vicki
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Joined: Mar 2008
Posts: 295
Third_Degree_AS_Kicker
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Third_Degree_AS_Kicker
Joined: Mar 2008
Posts: 295 |
Hmm... this is interesting. I'm the youngest in my line. Just myself and my sister though. (From my mom anyway---who I believe I get AS from)
Still no dx for me, but I'm 22 and I dread that I'm gettin there. Just no fusion yet.
My sis is healthy as can be. She has always been much more atheletic than me, and is considerably larger by build, not weight. I've always felt like abit of a runt next to her and my half-brother. I have always wondered if my small structure/small bones lead to worse joint pain. It's almost like my tiny ankles, etc. can't handle the pressure. Maybe my size contributed to the beginning of the AS? hmmm....
Interesting addition James. : )
Aly
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Joined: Nov 2003
Posts: 8,190
Very_Addicted_to_AS_Kickin
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Very_Addicted_to_AS_Kickin
Joined: Nov 2003
Posts: 8,190 |
Not sure we haven't blown this theory..lol
I am 2nd born.
Have 3 birth children who are all showing signs of AS
We have decided that we think MY AS came from my Dad's signs as just now at 73 he is showing signs and he is 5th out of 6 children.
Lisa
Speak kindly, Live simply, Care deeply, Love generously, and BLAH, HA, HA, LOUDLY! every chance you get.
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