I've just noticed no benefit whatsoever from being on humira and enbrel. It may sound strange but I almost feel as though I feel a little bit better when I'm not on them. If the Anti-TNF target a specific part of the immune system which is responsible to inflammation and pain related to Ankylosing Spondylitis, why is it that some people don't respond to these drugs? Lets say it works well for one person but doesn't work for another. Why is this the case when effectively the drug is targeting the same thing in both people with the same condition? Is it possible that a person can have a combination of more than one type of arthritis which makes their situation more severe? I have a family history of AS and rheumatoid arthritis so perhaps I am battling both?
It is so difficult coming to the realization that there are no more treatment options for me and I'm also at the stage where I have to start looking at living away from home and trying to get full time job. The thought of working 8-9 hours a day is daunting proposition when currently sitting down for more than 30 minutes is typically a nightmare situation. It's sad to admit it but getting through a 3 hour school day is a big accomplishment for me. It is a scary thought, but I guess it is just a case of one day at a time. Just gotta take each day as it comes and hopefully I will find something that will help me in the future.
Seb
