Kickas.org Forums Ankylosing Spondylitis General Discussion #1 AS Web Support Group compounding Antibiotics

For those NSDers and Antibiotic users...

what do u get your antibiotics compounded with?

i would prefer that it was just the drug but pharmacist says he HAS to put a filler in

I have problems with maize starch that is used as a filler with a lot of pills, so always have to check the labels. The liquid options are sometimes the easiest for me. If you have a choice, there are a variety of things that get used as fillers - you want to avoid maize starch, and probably microcrystalline cellulose (a highly processed form of starch), but lactose is fairly common as a filler, and if you want an inert filler, then talc could also be used.

Just be aware though that sometimes the fillers are chosen for particular properties, and you need them to help get the drug absorbed in the right way in your body. If you did just take the pure drug, my guess is that most of it would end up hitting your mouth and throat hard and not necessarily getting absorbed in the best way.

Hi, sunnypower:

Take the pharmacist some Bentonite powder and ask him to use it as 'filler.'

However, despite how strict I was otherwise, pills were often my greatest source of starches. Once I reacted very strongly to the teeniest capsules of boron that had just such a small amount of potato starch that I never would have thought I would react to it. It demonstrated to me just how disciplined we need to be at first.

There are some things that we cannot avoid and this is one reason antibiotics should be employed in the management of AS.

If You have tested some foods that might contain a little starch, it is sometimes-rarely also important to know the characteristics of that food. Garlic might be a prime example in that some parts are quite starchy, but perhaps the overall effect of the food as a "natural antibiotic" will mean that garlic despite some starch, would not be a good substrate for the bacterium, even if it were more starchy.

The point is, at some risk it is still worth it to have some certain foods and pills. I think sulfasalazine is also compounded with starch binders--and we sure have to take a lot of that stuff (3.5g/daily at therapeutic levels), but it is worth it if the drug helps, overall.

So, if the pharmacist really does not want to use a fair or inert filler (mushroom flour?), go ahead and still take the capsules; they will still help very much in this case. I buy commercial antibiotics and don't bother testing them even--all have worked except for one bad batch when I was doing the methodical date-coded evaluations. I was able to quickly identify that batch and switch to another.

Good Luck with it--
John

THANK YOU!!!

ill check out the powder u mention and see if he will do it. right now my doxy is compounded with acidophilus. not sure this is proper but its what doc ordered to avoid starch. im also unsure if the doxy is generic or pelletized so i shall find out.

been on it mwf for a month now without noticable improvement so she said shed do some flagyl for me and maybe switch to mino. well see.

she mentioned using AB IV on me. ever heard of benefits from this? i cant remember name of drug. she said shed learn more about whether it would be right for me or not and maybe give it a try. she said it would work in the gut and leave, it does not linger in the body.

thanks again for your valuable info john

Hey, sunnypower:

Well, when combined with diet, You should have very distinct results within four days, if the antibiotic were going to help enough--at least this has been my own experience and it does have a logical explanation--the IgA-Kp have a half-life of 100 hours. I did not have real good results with doxy, but it did work, albeit then upset my stomach too much; tetracycline was much easier on me and I took the dosages (500mg X 3) about 15-30 minutes before each of three largest meals. Very effective.

An iv antibiotic can help very much, but it must have anti-Klebsiella activity or it would be useless. A drug that does not linger in the body is Rifaximin, but it is not delivered iv, that I know about...

Flagyl would be WONDERFUL, even in combination with the doxy. I have never heard of acidophilus to compound with an antibiotic; the concept is weird--a probiotic plus an antibiotic. Ok as long as it works I suppose.

Good Luck
and Good HEALTH,
John

well i got flagyl 500mg 2x/day/10 days. sound good? got mino for after flagyl. i just got reg, no compound but dr said if it doesnt seem to go then she would re-script to be compounded.

i just took a doxy today. prob shouldnt have. maybe i wait a few days to start flagyl.

he will do bentonite if need be. thank u for that... and all your other help too!

sunny

Hi, sunny:

Don't worry about taking the Flagyl along with doxy; they are sometimes used together although Cipro plus Flagyl is more common. In some of us, Flagyl is a very harsh thing, but if You can get through a few courses it might help very much, even long-term.

You are welcome for everything; don't hesitate to ask here or in NSD forum.

HEALTH,
John

i think im going to start tomorrow on flagyl. a little nervous though, they are starchy tablets! we shall see how it goes.. fingers crossed for great results.

thanky