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Joined: Jan 2004
Posts: 9,848 Likes: 6
Very_Addicted_to_AS_Kickin
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OP
Very_Addicted_to_AS_Kickin
Joined: Jan 2004
Posts: 9,848 Likes: 6 |
http://www.musculoskeletalnetwork.com/rheumatoid-arthritis#panel1-7We routinely treat disorders such as rheumatoid arthritis, lupus, scleroderma, and ankylosing spondylitis with immuno-suppressive drugs. Yet if infection were known to be the root cause, this course of action would seem counterintuitive, if not potentially dangerous in the short or long run. This provocative essay by Stephen Paget MD of the Hospital for Special Surgery raises a provocative question or two. Who do you think is on the wrong track: Paget, or rheumatology? Weigh in with your opinion at the end of the article. The Microbiome and Autoimmunity: Seven Signs of Impending Paradigm Change Musculoskeletal Network, March 19, 2013 
MollyC1i - Riding OutAS
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Joined: Oct 2012
Posts: 190
First_Degree_AS_Kicker
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First_Degree_AS_Kicker
Joined: Oct 2012
Posts: 190 |
Your link doesn't send me to any article for some reason.
From what I understood of Dr. Paget's work, he thinks that AS might be the result of one' incapability of clearing unwanted micro-organism from the body and that perhaps we should be enhancing the immune system and not suppressing it.
Who knows... Surely someone did some research on that theory?
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Joined: Jan 2004
Posts: 9,848 Likes: 6
Very_Addicted_to_AS_Kickin
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OP
Very_Addicted_to_AS_Kickin
Joined: Jan 2004
Posts: 9,848 Likes: 6 |
Possibly need to sign in to read the article? It is a freeby - though I haven't yet read the whole article - but here you are :- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540616/
Last edited by MollyC1i; 06/26/13 07:33 AM. Reason: for link to article
MollyC1i - Riding OutAS
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Joined: Sep 2007
Posts: 608
Master_Sergeant_AS_Kicker
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Master_Sergeant_AS_Kicker
Joined: Sep 2007
Posts: 608 |
For patients with these autoimmune / auto-inflammatory diseases it's not as simple as treating them in such a way as to resolve an infection. Their body is reacting to a component or components of the gut microbiome as if it were an infection but very often the "target" is considered part of the normal gut flora. These patients have a genetic weakness such that a dietary strategy like LSD or NSD might help alleviate symptoms but perhaps not completely resolve the disease. In the face of symptoms such as knee synovitis DMARD's might help control symptoms, simplistically by dampening down inflammation by suppressing an out of control immune response.
Dx Oct 2006 B27+ undifferentiated spondlyarthropathy (uSpA) with mild sebhorrhoeic dermatitis and mild Inflammatory Bowel Disease (IBD) controlled by NSD since 2007.
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