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I've been taking Enbrel for one month now and (knock on wood) I have not had any side effects. I don't know where you're located, but there was a nasty sore throat bug going around Massachusetts at the end of June this year. Hopefully it's just a coincidence. I'm getting so much relef from the Enbrel that I'd almost be willing to say that I'd endure a sore throat every day for the rest of my life if I had the choice between that and Enbrel. The stuff is working really well for me. Good luck and keep us posted on your results!