It's possible there is something in the filler that is causing a bad reaction, but since "muscle stiffness" was listed as a potential side effect it's probably the LDN.
There is one other treatment I've heard helps some MS patients a lot, which is a special multi-phase antibiotic treatment. It probably doesn't help everyone, because there are likely different root causes, but it seems that some people get "autoimmune" diseases like MS when tricky bacteria are hidden out in their cells (so-called cryptic infections). Here is a web site that focuses on a common type of bacteria that has this capability to hide out inside the body and cause autoimmune symptoms:
http://cpnhelp.org/
