Hi, Mandy,
And welcome to KickAS!
I don't know whether people develop immunity to Enbrel or not. I'm just asking to see if anyone else may have heard about this. I've been on Enbrel for a year and it has truly been a miracle for me. I felt the effects of it right away. What I'm going through now may just be a weird flare. I'm glad your husband was able to get off methotrexate, it's hard on the liver. Other than what I'm gong through now, I have had no side effects from Enbrel.
Post on the main forum; more will see your post and respond.
Hugs,
Cindy
Life may not be the party we hoped for, but while we are here we might as well dance.